OB/GYN Clinical Alert – April 1, 2006
April 1, 2006
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Diagnostic Open Laparoscopy in the Management of Advanced Ovarian Cancer
Optimal surgical cytoreduction is a recognized staple of initial advanced ovarian cancer care. However, within the spectrum of patients who undergo this surgery are those in whom complete resection is either impossible or unwarranted in the face of certain unacceptable morbidity. -
EVRA and Venous Thrombosis
Jick and colleagues, epidemiologists at Boston University School of Medicine, performed a case-control study of nonfatal venous thrombosis using information derived from a very large database that records prescriptions and diagnoses longitudinally in managed health care plans. -
Randomized Double-Blind Trial of Estrogen Replacement Therapy vs Placebo in Stage I or II Endometrial Cancer
The association between exogenous estrogen use and endometrial cancer development has been well documented. Nonetheless, the hazard of estrogen replacement therapy in women with a personal history of endometrial cancer has not been well studied and, despite anecdotal evidence of its safety, is largely discouraged among clinicians. -
The WHI Studies on Calcium and Vitamin D
The Womens Health Initiative (WHI) conducted a randomized trial of Calcium and Vitamin D supplementation.1 The 36,282 postmenopausal women were part of the WHI clinical trials involving postmenopausal hormone therapy or dietary modification. The average follow-up was 7 years; 37% of the women were age 50 to 59, 45.5% were 60 to 59, and 17.5% were 70 to 79. -
Assisted Reproductive Technology and Pregnancy Outcome
In November the authors of the now famous FASTER trial, which was initially focused on the use of nuchal translucency (NT) in the first trimester, published one of many spin-off reports. -
Pharmacology Watch: Can Calcium and Vitamin D Prevent Hip Fractures?
Treatment of Benign Prostatic Hyperplasia; Treatment of Osteoarthritis of the Knee; Refractory Asthma and TNFConnection?; FDA Actions -
Clinical Briefs in Primary Care supplement