OB/GYN Clinical Alert – September 1, 2003
September 1, 2003
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Postmenopausal Hormone Therapy and Coronary Heart Disease
The WHI and the WELL-HART clinical trials report that hormone therapy does not reduce the risk of coronary events or slow the progression of atherosclerosis in older women. -
12 vs 3 Months of Maintenance Paclitaxel in Patients with Advanced Ovarian Cancer after Platinum and Paclitaxel-Based Chemotherapy
Twelve cycles of single-agent paclitaxel administered to women with advanced ovarian cancer who attain a clinically defined complete response to initial platinum/paclitaxel-based chemotherapy significantly prolongs the duration of progression-free survival. -
Fetal Assessment Comparing Nonstress Test with Umbilical Artery Doppler Velocimetry
Umbilical artery Doppler as a screening test for fetal well-being in a high-risk population was associated with a decreased incidence of cesarean delivery for fetal distress compared to the nonstress testing, with no increase in neonatal morbidity. -
Ultrasound Evaluations of Cervical Length in Preterm Labor
In women with threatened preterm labor, sonographic measurement of cervical length helps distinguish between true and false labor. -
Pharmacology Watch: Study Shows Oral IIb/IIIa Receptors Increase Mortality
Another study has shown an increase in mortality associated with the use of an oral IIb/IIIa receptor antagonist. -
Clinical Briefs in Primary Care Supplement