Neurology Alert – December 1, 2016
December 1, 2016
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Migraine Prophylaxis in Children
In a randomized, double-blind, placebo-controlled trial of migraine prophylaxis in children ages 8-17 years, treatment with neither amitriptyline nor topiramate showed significant differences in headache frequency or headache-related disability compared to placebo.
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Cognition in Older Migraine Sufferers: The Data Are Not Clear!
Older migraineurs, particularly migraineurs with aura, tend to score higher in tests of executive functioning and fine motor skills than do non-migraineurs. However, the lack of a detailed analysis of an unrepresentative headache population may confound the conclusions.
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Prognosticating Ulnar Neuropathy at the Elbow
In a large retrospective review of treatment outcome for ulnar neuropathy at the elbow, no difference was found in outcomes between any of the various conservative or surgical therapies, but prognosis was determined by the severity of the lesion at time of diagnosis.
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Disability in Patients with Multiple Sclerosis: A Long-Term Study
SYNOPSIS: In a long-term study, the rate of disability progression in treated relapsing and progressive, multiple sclerosis patients was lower than that reported in earlier natural history studies.
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Time to Treatment with Endovascular Thrombectomy Remains a Critical Variable
this meta-analysis of thrombectomy in patients with large vessel ischemic stroke demonstrated that earlier treatment compared with medical therapy alone was associated with lower degrees of disability at three months.
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Pulmonary Embolism Common Cause for Syncope in Hospitalized Patients
A recent review of clinical features of patients with syncope found that pulmonary embolism may be one of the most common causes, and thus should be considered by all physicians who are evaluating such patients.
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Intensive Blood-pressure Lowering in Acute Intracerebral Hemorrhage
Treatment of patients with intracerebral hemorrhage with an intensive blood pressure-lowering regimen did not result in a lower rate of death or disability than standard reduction to a target systolic blood pressure of 140-179 mmHg.
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Basilar Artery Thrombectomy Can Be Accomplished with Acceptable Outcomes
A recent study found that mechanical thrombectomy for basilar artery occlusion can be accomplished with a similar success rate as that which has been published in large multicenter, randomized trials of thrombectomy.