Neurology Alert – December 1, 2015
December 1, 2015
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Medication for Acute Low Back — A Randomized Clinical Trial
In a trial comparing naproxyn alone to combinations with cyclobenzaprine or oxycodone/acetaminophen in patients with acute low back pain, there was no difference in outcome after 1 week.
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Clinical Features and Consequences of Inclusion Body Myositis
Inclusion body myositis, while poorly understood regarding cause, is clearly responsive to physical exercise, and patients should be encouraged to maintain robust physical activity.
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Neonatal MRI Can Predict Future Academic Difficulties for Children Born Preterm
Neonatal brain MRI can identify structural changes that predict future difficulties in school performance for children who are born preterm.
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Selective Disruption of Thalamo-Cortical Connections in Patients with Disorders of Consciousness — a Possible Biomarker for Cognitive-Motor Dissociation
In this case-control, functional neuroimaging study, the authors developed a novel method to evaluate correlations between integrity of neural circuits involved in overt and covert motor behavior and apply the method to two patients: one with a dissociation of imaging-based vs bedside evidence of command following and one without.
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Postmortem Evidence of Limbic, Neocortical, and Basal Ganglia Deficits in Parkinson’s Disease Dementia
Postmortem brain tissue from 15 individuals with Parkinson’s disease dementia was analyzed by high-performance liquid chromatography and immunoassays, revealing widespread deficits in dopamine, serotonin, and noradrenaline innervation.
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Carotid Occlusion Rarely Develops from Asymptomatic Carotid Artery Stenosis
The risk of progression to carotid occlusion is well below the risk of carotid stenting or carotid endarterectomy, and intensive medical therapy appears to be preferred for the vast majority of patients with asymptomatic carotid artery stenosis.