Neurology Alert – November 1, 2015
November 1, 2015
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Autoimmune Cerebellar Ataxia — Responses to Treatment
This study analyzed patients diagnosed with antibody-mediated paraneoplastic and non-paraneoplastic cerebellar ataxia, and treatment benefit was seen predominantly in the non-paraneoplastic group.
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Potential Imaging Biomarkers of SUDEP: Can We Predict Sudden Death in Epilepsy?
The authors retrospectively conducted a voxel-based analysis of T1 MRI scans to compare gray matter volumes in 12 cases of sudden unexpected death in epilepsy (SUDEP) acquired at a median of 2 years before death with patients at high or low risk for SUDEP and with healthy controls, and demonstrated significant anatomical differences between the groups.
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Lower Risk of Parkinson’s Disease After Vagotomy: Implications for Spread of Pathology
Truncal vagotomy was associated with a reduced risk for Parkinson’s disease with a hazard ratio of 0.58 for those with more than 20 years’ follow-up. This suggests the vagus nerve as a possible route of entry into the central nervous system for this neurodegenerative process.
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Botulinum Toxin and Treatment of Spasticity
AbobotulinumtoxinA is effective at reducing spasticity and reducing disability in patients with upper limb spasticity due to stroke or traumatic brain injury.
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Treatment for Ulnar Neuropathy at the Elbow
In a randomized treatment trial of steroid injection into the cubital tunnel for ulnar neuropathy, there was no difference in outcome compared to placebo.
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Every 5-minute Delay in Performing Endovascular Reperfusion Results in 1 out of 100 Patients Having a Worse Disability Outcome
Every 5-minute delay in performing endovascular reperfusion results in 1 out of 100 patients having a worse disability outcome.