Neurology Alert – July 1, 2015
July 1, 2015
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Serum and CSF Biomarkers of Brain Injury After Sports-related Concussion
ABSTRACT & COMMENTARY: So far none of the currently measured biomarkers has sufficient sensitivity or specificity to be clinically useful.
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Cerebrospinal Fluid Biomarkers of Neuronal Injury in Mild AD
Cerebrospinal fluid visinin-like protein 1 is a useful marker, along with CSF tau and phospho-tau measurements, to predict brain atrophy and neurodegeneration in patients who carry a clinical diagnosis of Alzheimer’s disease.
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Prevalence of Rest Tremor in Essential Tremor
Rest tremor is seen in patients with more advanced essential tremor, yet its prevalence varies significantly between patient groups.
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Diagnosing POLG-related Diseases
Mutations of the polymerase-gamma subunit in mitochondrial DNA is a common cause of adult mitochondrial syndromes, such as myopathies, encephalopathies, epilepsy, and ataxias.
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Can Dietary Intervention Delay the Onset of Alzheimer’s Disease?
In a prospective study of an elderly population, moderate adherence to the MIND diet was associated with a 53% reduction in the development of Alzheimer’s disease.
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Consequences of Intracerebral Hemorrhage in Young Adults
Intracerebral hemorrhage accounts for 10-20% of all strokes in North America and Europe, with an overall incidence of 25 cases per 100,000 population annually. In this study, the authors evaluated the long-term survival and recovery of 268 1-month survivors ages 16-49 years to assess the prognosis of intracerebral hemorrhage in the younger group.
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Convexal Subarachnoid Hemorrhage and Amyloid Angiopathy
Cerebral amyloid angiopathy is emerging as a major cause of spontaneous intracerebral hemorrhage in the elderly. The authors of this study undertook a careful review of all of the patients in their database over a 9-year period who had spontaneous convexal subarachnoid hemorrhage, and they performed a careful longitudinal analysis of clinical and neuroimaging data.