Neurology Alert – December 1, 2002
December 1, 2002
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Ruptured Aneurysm: Clip or Coil? Superiority of Endovascular Treatment Continues to Mount
The ISAT trial enrolled 2143 patients, primarily in Britain, with ruptured intracranial aneurysms and randomly assigned them to neurosurgical clipping or GDC coils. The results add another nail into the coffin of neurosurgical clipping. -
Mitochondrial Defects Play Role in Parkinson’s Disease
There is substantial evidence that mitochondrial defects and oxidative damage play a role in the pathogenesis of Parkinsons disease. -
West Nile Virus’ Spread Tracked Across United States
West Nile virus, otherwise called West Nile encephalitis, has slowly become a growing American and Canadian viral disease since its first apparent invasion into the Western Hemisphere in 1999. -
Very Mildly Demented Patients Can Draw Clocks
In a longitudinal study of 75 patients that included 25 with the earliest detectable stage of dementia, Powlishta and colleagues found that clock drawing had unacceptably low sensitivity in detecting the very earliest stages of Alzheimer's disease. -
Valproate for Diabetic Painful Neuropathy
Diabetic painful sensory neuropathy remains difficult to treat. In this randomized, double-blind, placebo-controlled trial, sodium valproate was administered to 30 patients with efficacy and safety compared to 30 placebo-control patients. -
A New Treatment for Left Spatial Neglect After Stroke
Schindler and colleagues in Munich evaluated whether visual exploration training alone or in combination with electromechanical vibration of the left neck muscles of patients while they engaged in visual search exercises were effective techniques for the rehabilitation of spatial neglect. -
Pharmacology Watch: FDA Approves Generic Version of AstraZeneca’s Prilosec
FDA Approves Generic Version of AstraZenecas Prilosec; Pegasys Approved To Treat Hepatitis C; HRT Reduces Alzheimers Risk, Study Says; Heparin Plus Alteplase More Effective; Digoxin Effects Differ By Sex; McClellan Named FDA Commissioner; FDA Actions -
Clinical Briefs in Primary Care Supplement
Vitamin-Mineral Supplementation and Acute RTI in Elderly; B-Type Natriuretic Peptide Levels and Outcome in Heart Failure; Companion Influence During Primary Care Encounters; Handrubbing with Alcohol-Based Solution vs. Standard Handwashing; Program To Prevent Functional Decline in Frail Elderly Who Live at Home; Treatment of Diabetic Neuropathy with Isosorbide Dinitrate Spray