Neurology Alert – March 1, 2011
March 1, 2011
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Treating Active Neuromyelitis Optica with Mitoxantrone
Twenty highly active patients with neuromyelitis optica (NMO) stabilized after treatment with mitoxantrone. All patients tolerated treatment without significant safety concerns. Mitoxantrone may be an option for NMO given its differential inhibitory effect on subsets of B-cells. -
Early Aggressive Therapy for Myasthenia Gravis
Early plasmapheresis and high-dose intravenous corticosteroids may be as effective as conventional oral corticosteroid therapy in the treatment of myasthenia gravis. -
Hold Your Applause! A Critical Reappraisal of the Applause Sign
The applause sign is a nonspecific indicator of frontal lobe dysfunction and is not specific to Parkinsonian disorders. -
Is Vitamin D Important in the Prevention of Dementia?
Severe Vitamin D deficiency appears to worsen dementia and supplementation may be beneficial. -
Which Way is Up?
A novel technique used to study deviations in the subjective visual vertical may assist in the localization of brainstem lesions. -
Stroke Alert: A Review of Current Clinical Stroke Literature
Controversy remains regarding the optimal blood pressure early in the course of ischemic stroke. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
Escitalopram for menopausal hot flashes, rifaximin for IBS without constipation, herpes zoster vaccination, antiepileptics drugs and fracture risk, and FDA Actions.