Neurology Alert – July 1, 2012
July 1, 2012
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Primary Progressive Apraxia of Speech: A Distinct Disorder
Primary progressive apraxia of speech has been well characterized as a distinct neurodegenerative disease, but underlying pathology and prognosis are uncertain in most cases. -
New Therapies for Tinnitus
It is recognized that most cases of chronic tinnitus are generated by central brain mechanisms that may be amenable to treatment with cognitive therapies and magnetic stimulation protocols of the temporal and frontal lobes. -
Predicting Response to IVIG or Plasmapheresis in Myasthenia Gravis
Clinical examination severity appears to be the best predictor of response to immunotherapy in patients with myasthenia gravis. -
An Advance in the Search for Parkinson's Disease Biomarkers
Changes in CSF metabolites reflect dopamine and norepinephrine deficiency in Parkinson's disease, and may be sensitive in early identification. -
Outcome of Shunting for Idiopathic 'Normal Pressure Hydrocephalus'
Normal pressure hydrocephalus remains a clinical diagnosis and standardized clinical assessments predict a positive response to shunting in most patients. -
Stroke Alert: A Review of Current Clinical Stroke Literature
Over a 6-year period, 2305 patients with reduced left ventricular ejection fraction and normal sinus rhythm were randomized to warfarin treatment (target INR of 2.0 to 3.5) or aspirin (325 mg per day) and followed to determine the rate of a composite endpoint of ischemic stroke, intracerebral hemorrhage, or death from any cause. -
Clinical Briefs in Primary Care Supplement
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Pharmacology Watch
Azithromycin and cardiac risk; warfarin and heart failure; aspirin and VTE; effectiveness of long-acting contraceptives; and FDA actions.