Neurology Alert – August 1, 2008
August 1, 2008
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Lymphoma and Neuropathy
In patients with lymphoma, demyelinating neuropathy is usually associated with Hodgkin's lymphoma, whereas polyradiculopathy is usually caused by high-grade B-cell lymphoma. -
Ketogenic Diet is Effective for Childhood Epilepsy
The ketogenic diet was beneficial in children with medically refractory epilepsy in this randomized controlled trial. -
Spontaneous Spinal Fluid Leak Headaches: Detection, Definition of the Diagnosis
Specific radiological criteria and response to epidural blood patching can confirm the diagnosis of spontaneous spinal CSF leaks and intracranial hypotension. Non-invasive magnetic resonance myelography can detect the site of CSF leakage. -
Small Fiber Neuropathy: Making the Diagnosis
In the setting of chronic pain in a pattern consistent with polyneuropathy, determination of intraepidermal nerve fiber density (IENFD) is the most sensitive diagnostic test. -
Is High-Dose Cyclophosphamide a Treatment Option for Multiple Sclerosis?
Clinical stabilization was achieved after the treatment with high-dose cyclophosphamide (Cy) therapy in a small cohort of active relapsing-remitting multiple sclerosis (MS) patients. -
How Often Does Mild Cognitive Impairment Progress to Alzheimer's Disease?
Over a 5-year period, 16% of elderly people developed mild cognitive impairment (MCI) and had double the risk of developing Alzheimer's disease (AD) than normals; however, 30% with MCI reverted to normal. -
Pharmacology Watch
Baxter Bioscience has developed a whole-virus, two dose vaccine against avian flu; warning label now on antipsychotics regarding an increased risk of mortality in elderly patients treated for dementia-related psychosis; vitamin D for men with heart disease on horizon? A new oral anticoagulant may soon be available for prevention of thrombotic complications of hip or knee surgery; FDA Actions -
Clinical Briefs in Primary Care supplement