Neurology Alert – March 1, 2005
March 1, 2005
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Conflicting Data on Benefit of IVIG Treatment in MS
Intravenous immunoglobulin treatment for the first year from onset of the first neurological event suggestive of demyelinative disease significantly lowers the incidence of a second attack and reduces disease activity as measured by brain magnetic resonance imaging. -
High Homocysteine and Stroke: Cause or Effect?
The observed increase in risk of stroke among individuals homozygous for the MTHFR T allele is close to that predicted from the differences in homocysteine concentration conferred by this variant. -
Do Autoantibodies Cause Narcolepsy?
IgG from all narcolepsy patients significantly enhanced bladder contractile responses to the muscarinic agonist carbachol and neuronally released acetylcholine, as compared to the control IgG. -
Extraocular Muscle Susceptibility in Neuromuscular Disease
Extraocular muscles have fundamentally distinct structural, functional, biochemical and immunological properties compared to other skeletal muscles. While these properties enable high fatigue resistance and the rapid and precise control of extraocular motility, they might also explain why extraocular muscles are selectively involved in certain disorders, such as chronic progressive external ophthalmoplegia, myasthenia gravis, and Graves ophthalmopathy. -
Anti-MAG or Not?
Pure sensory clinical phenotype, low median and ulnar terminal latency index, and absence of M responses in the lower limbs were significantly associated with the diagnosis of MAG-PN, and indicate a moderate to large increase in probability of this diagnosis in patients with chronic dysimmune demyelinating polyneuropathies. -
Primary Generalized Dystonia: Encouraging Results For Deep-Brain Stimulation
The findings support the efficacy and safety of the use of bilateral stimulation of the internal globus pallidus in selected patients with primary generalized dystonia. -
Surgery For Epilepsy: Stratifying Outcome in Patients With Hippocampal Sclerosis
Epilepsy duration is the most important predictor for long-term surgical outcome. -
Pharmacology Watch: The Risk of Aspirin Withdrawal in ACS Patients
Stopping aspirin may be hazardous to your health, according to recent research. -
Clinical Briefs in Primary Care Supplement