Neurology Alert – December 1, 2005
December 1, 2005
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Pharmacology Watch
Beta-Blockers Therapy for the Treatment of Hypertension; Treatments for Acute Migraine; Statin Therapy for ACS Patients; The Correct Dosing for Onychomycosis; FDA Actions -
Clinical Briefs in Primary Care supplement
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Is Snoring a Risk Factor for Stroke?
In a prospective cohort study of 697 patients with obstructive sleep apnea followed for a median duration of 3.4 years, there was a significant association with stroke or death. -
Hyperglycemia Associated with Decreased Recanalization After IV t-PA in Acute Stroke
Recanalization after treatment with intravenous tissue plasminogen activator (t-PA) is more likely in acute stroke patients whose admission serum glucose is less than 158 mg/dL. -
HTLV-1 and the Peripheral Nervous System
Human T-cell lymphotropic virus type I (HTLV-1) is a human retrovirus and the etiologic agent for a progressive neurological disease called HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP). -
Strokes Too Mild for IV tPA May Still Have Severe Outcomes
A substantial minority of patients deemed too good for intravenous tPA were unable to be discharged home. -
Clopidogrel and Aspirin: New Data From COMMIT
In a wide range of patients with acute MI, adding clopidogrel 75 mg daily to aspirin and other standard treatments (such as fibrinolytic therapy) safely reduces mortality and major vascular events ... -
Pathophysiology of Muscle Cramps
Patients will benefit from further studies to better define the pathophysiology of muscle cramps and to find more effective medications with fewer side-effects. -
Topiramate for Migraine
Topiramate at a maintenance dose decreased the mean number of monthly headache days in children with frequent migraines. Tolerability of the medication in children was generally similar to placebo.