– April 1, 2003
April 1, 2003
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Limited Lung Resection and Brachytherapy May Benefit Cancer Patients Whose Lung Function is Compromised
The standard of care for early lung cancer is surgery. However, in aged or frail patients, or in those whose pulmonary or cardiac status is compromised, radical surgery may be contraindicated. -
Capecitabine with Gemcitabine for Advanced Pancreatic Cancer: Results from a Swiss Phase I/II Trial
Although gemcitabine has been proven to be of value in the treatment of advanced pancreatic cancer, remission rates remain low and survival is measured in weeks to months. Swiss investigators report the results from a phase I/II study of combined gemcitabine/capecitabine treatment. -
Tamoxifen Alone vs Adjuvant Tamoxifen for Operable Breast Cancer in the Elderly
Women older than age 70 comprise 15-20% of breast cancer patients. Some of these older patients may not be able to tolerate or do not desire the standard surgical procedures of either lumpectomy or mastectomy. -
Toward Developing a Rational Strategy for Advanced Lung Cancer Treatment in the Elderly
In a multicenter, Italian, randomized, phase III trial, single-agent vinorelbine or gemcitabine proved to be as effective as a combination of the 2 agents in the treatment of advanced non-small-cell lung cancer occurring in patients 70 years and older. -
Increased Risk of Breast Cancer with Estrogen-Progestin Therapy
Postmenopausal estrogen-progestin therapy increased the risk of breast cancer in a population-based cohort in Sweden, and estrogen-only did not. -
International Collaborative Ovarian Neoplasm Trial 1 and Adjuvant Chemotherapy In Ovarian Neoplasm Trial
Platinum-based adjuvant chemotherapy improved overall survival and recurrence-free survival at 5 years in this combined group of patients with early-stage ovarian cancer defined by the inclusion criteria of the ICON1 and ACTION trials. -
Clinical Briefs in Primary Care Supplement