Internal Medicine Alert – February 28, 2019
February 28, 2019
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Hormone Therapy and Mortality: No Overall Effect?
An evaluation of outcomes of users and nonusers of postmenopausal hormonal therapy followed longitudinally in the Danish database showed no overall difference in mortality.
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Caregivers and Mindfulness-Based Stress Reduction Interventions
A Cochrane Review regarding efficacy of mindfulness-based stress reduction (MBSR) for family caregivers of dementia patients revealed low-quality evidence that MBSR reduces short-term anxiety and depressive symptoms in this population.
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PCSK9 Inhibitors in Acute Coronary Syndrome Patients
Compared to adding placebo, using the proprotein convertase subtilisin/kexin type 9 inhibitor alirocumab in post-acute coronary syndrome patients on maximally tolerated, high-intensity statins with low-density lipoprotein (LDL) cholesterol levels higher than 70 mg/dL lowered LDL and reduced the number of major adverse cardiac events.
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Antipsychotics Do Not Shorten the Duration of ICU Delirium
In this randomized, placebo-controlled trial, neither haloperidol nor ziprasidone altered the duration of delirium when compared to placebo.
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Revefenacin Oral Inhalation (Yupelri)
Revefenacin should be used to help patients with COPD.