Internal Medicine Alert – October 30, 2018
October 30, 2018
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Carbohydrates, Insulin, and Obesity
Carbohydrate intake stimulates insulin secretion, which is the primary driver of weight gain. Besides driving glucose into cells, insulin causes fat storage, increases hunger, and lowers energy expenditure. High insulin blood levels lead to obesity with some genetic variation.
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Can Hormone Therapy Prevent the Development of a ‘Dowager’s Hump’?
Postmenopausal hormone therapy may reduce the risk of developing age-related hyperkyphosis, commonly known as a “Dowager’s hump.” Such therapy may provide long-term benefits.
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Coffee Consumption and Mortality
After rigorous evaluation using multiple statistics, an inverse relationship between coffee intake and all-cause mortality was demonstrated consistently across the racial/ethnic groups examined.
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Poor Sleep Can Lead to Accelerated Atherosclerosis
New data provide further support for the importance of sleep in the optimization of medical outcomes.
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Migalastat (Galafold) Capsules
Migalastat is indicated for the treatment of adults with confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant based on in vitro assay data.