Internal Medicine Alert – June 15, 2017
June 15, 2017
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Safe Treatment Recommendations for Benzodiazepine Dependence
There are clear, evidence-based treatment withdrawal regimens for benzodiazepine-dependent patients.
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Risk Factors for Hospital Readmissions Ending in Death or Transition to Hospice
In this retrospective cohort study, multiple factors were identified during initial hospitalization, including sepsis and shock, that were associated with a hospital readmission within 30 days resulting in death or transition to hospice.
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Fludrocortisone for Orthostatic Hypotension Associated with Parkinson’s Disease
This double-center, double-blind, randomized, controlled trial compared the efficacy of pyridostigmine bromide vs. fludrocortisone and demonstrated that pyridostigmine bromide was not as effective as fludrocortisone.
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Brigatinib Tablets (Alunbrig)
Brigatinib is indicated for the treatment of patients with anaplastic lymphoma kinase-positive metastatic non-small cell lung cancer who have progressed on or are intolerant to crizotinib.
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Clinical Briefs
In this section: drug therapy for diabetes; timing surgical knee and hip replacement; and treating low back pain.
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Should the Treatment Response Cause Alarm?
The rhythm in the figure was observed as a previously healthy young adult was receiving treatment for the patient described as 'palpitations.'