Internal Medicine Alert – December 30, 2015
December 30, 2015
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Is it Normal Aging or Chronic Kidney Disease?
Current clinical guidelines for the diagnosis of chronic kidney disease resulted in more than half of adults > 70 years of age having chronic kidney disease. Should these guidelines change to require age calibration for diagnosis and classification of chronic kidney disease?
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Vitamin D Levels and Cognitive Function: Does It Make a Difference?
Similar to previous studies, vitamin D deficiency and insufficiency rates were not significantly different between those with normal cognitive status, mild cognitive impairment, or dementia. However, cognitive decline occurred at a significantly greater rate in individuals with low 25-hydroxyvitamin D levels in the areas of episodic memory and executive function.
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Nicotinamide Chemoprevention for Skin Cancer Is Impressive
In a Phase III, double-blind, randomized, placebo-controlled trial, oral nicotinamide was safe and effective in reducing the rates of new nonmelanoma skin cancers and actinic keratoses in high-risk patients.
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Naloxone Nasal Spray (Narcan)
The FDA has approved naloxone in the form of a nasal spray as a life-saving medication to reverse the effects of an opioid overdose.
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No More Bacon? Carcinogenicity of Meat
A review of published research by the World Health Organization concludes that processed meats are probably carcinogenic.
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Clinical Briefs
In this section: no payoff to physical therapy after healed ankle fracture; bisphosphonates and bone recurrence; and manipulating the microbiome.