Internal Medicine Alert – June 30, 2015
June 30, 2015
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Can CPAP Treatment Prevent Dementia?
ABSTRACT & COMMENTARY: Older people with sleep apnea had onset of cognitive decline at an earlier age than those without sleep apnea.
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Obesity Paradox and Diabetes
In a prospective cohort study of overweight or obese type 2 diabetics, being overweight was associated with a lower mortality risk, but being obese was not.
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PCSK9: A Major New Advance in Cholesterol-lowering Therapy
When added to statin therapy at the maximum tolerated dose, the PCSK9 inhibitor alirocumab reduced low-density lipoprotein cholesterol levels by 62% and also reduced the rate of occurrence of cardiovascular events.
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Pharmacology Update: Memantine HCl and Donepezil HCl Capsules (Namzaric™)
The addition of memantine to a stable dose of an acetylcholinesterase inhibitor may improve cognitive performance.
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Clinical Briefs
Updates on treatment of depression, the prevention and treatment of osteoporosis, and subclinical thyroid dysfunction as it relates to fracture risk.