Internal Medicine Alert – November 15, 2004
November 15, 2004
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Risk of Community-Acquired Pneumonia and Use of Gastric Acid-Suppressive Drugs
Current use of gastric acid-suppressive therapy was associated with an increased risk of community-acquired pneumonia. -
Hemoglobin A1c: It’s Not Just for Diabetics Anymore
The relative risk for each 1% increase in hemoglobin A1c was 1.3 for CHD, 1.2 for CVD, and 1.2 for all cause mortality. -
Influenza A Resistant to Oseltamivir
Oseltamivir treatment of children with influenza A virus infection was associated with the selection of resistant mutants in 18%. -
Better Shoulder Outcomes with Spinal Manipulative Therapy
Adding early manual manipulation of the cervicothoracic spine for shoulder pain or dysfunction disorders, in addition to regular care of information, advice and medications, produced much better recovery at both 12- and 52-weeks post treatments. -
Pharmacology Update: Hydromorphone Extended-Release Capsules (Palladone) (C-II)
The FDA has approved a new formulation of hydromorphone for the management of pain. -
Clinical Briefs
Agents which alter cardiac repolarization have been associated with torsades de pointes. -
ECG Review: A Most Common Oversight
The ECG in the Figure was interpreted as showing sinus tachycardia with non-specific ST-T wave abnormalities. Do you agree? -
Pharmacology Watch: The FDA and Merck Fielding Concerns About Vioxx
Merck announced on September 30th that it is voluntarily withdrawing rofecoxib (Vioxx) from the worldwide market.