Internal Medicine Alert – July 15, 2010
July 15, 2010
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Metformin Doesn't Play Nice with B12
Vitamin B12 levels fall, and continue to fall, with continued metformin use in patients already receiving insulin. -
Testing for Celiac Disease
Testing patients with abdominal symptoms for celiac disease in primary care settings using IgA tissue transglutaminase antibodies and IgA endomysial antibodies yielded high sensitivity and specificity, justifying their use widely for diagnosis. -
High-dose Vitamin D and Risk of Falls
In community-dwelling women age 70 years and older, annual oral administration of high-dose vitamin D for 3-5 years resulted in a higher, not lower, incidence of falls and fractures. -
Ketorolac Tromethamine Nasal Spray (Sprix™)
Ketorolac nasal spray is indicated for the management of moderate to moderately severe pain that requires analgesia at the opioid level.1 It is indicated for short-term use only (up to 5 days). -
Clinical Briefs by Louis Kuritzky, MD
Because it is recognized that type 2 diabetics (DM2) incur greater risk of CV outcomes than the general population, consensus groups have advocated BP < 130/80 mmHg as a preferred goal, in contrast to 140/90 mmHg for the general hypertensive population. -
ECG Review: Is There a Grouping?
The ECG shown above was obtained from an 88-year-old woman who refused treatment. What is the rhythm? Is there a grouping? Is anything else going on? -
Pharmacology Watch
New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions.