Internal Medicine Alert – February 28, 2013
February 28, 2013
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Risk of Bleeding with Warfarin Therapy for Atrial Fibrillation
The authors conclude that in a large cohort of older patients with atrial fibrillation, hemorrhage is common during both the first 30 days and subsequent months of warfarin therapy, and is related to risk factors in the CHADS2 score and also to age. -
Mammography: Does Early Detection Matter?
Although widespread screening mammography has greatly increased the diagnosis of early breast cancer, it has had only a marginal effect on the diagnosis of late-stage tumors and breast cancer mortality. -
Risk of Angioedema with Drug Therapy
The authors concluded that compared to beta-blockers, the risk of angioedema is highest with ACEIs or aliskiren and lowest with ARBs. -
Physicians' Own Beliefs on Goals of Care Influence Presentation of Comfort Care Option to Patient Surrogates
During family discussions, physicians who believe more strongly that life support should be withdrawn are more likely to present the option of comfort care and describe its benefits. -
Pharmacology Update: Lomitapide Capsules (Juxtapid)
The first inhibitor of the microsomal triglyceride transport protein (MTP) has been approved for the treatment of homozygous familial hypercholesterolemia (HoFH). -
Clinical Briefs By Louis Kuritzky, MD
CKD: Consistency of GFR and Albuminuria as Risk Predictors; Changing Outcomes for Patients with Chronic Hepatitis C; Is Fructose a Primary Culprit in Obesity?