Internal Medicine Alert – May 30, 2005

May 30, 2005

• What You Can't See Will Hurt You (and Your Patient)

  Concealed renal insufficiency is common and contributes to adverse drug reactions from hydrosoluble medications.

  Read more about What You Can't See Will Hurt You (and Your Patient) - Internal Medicine Alert – May 30, 2005

• Asymptomatic Mitral Regurgitation: When is it Appropriate to Repair or Replace?

  Patients with an effective regurgitant orifice of at least 40 mm² should promptly be considered for cardiac surgery.

  Read more about Asymptomatic Mitral Regurgitation: When is it Appropriate to Repair or Replace? - Internal Medicine Alert – May 30, 2005

• Special Report: Bad News About the COX-2 Inhibitors

  There has been enormous controversy regarding the benefit/safety relationship of the COX-2 inhibitors, which were initially introduced in 1999. This is a cautionary tale.

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• Pharmacology Update: Micafungin Infusion (Mycamine^TM)

  The FDA has approved a new intravenous antifungal agent.

  Read more about Pharmacology Update: Micafungin Infusion (Mycamine^TM) - Internal Medicine Alert – May 30, 2005

• Clinical Briefs

  Management of asthma in America remains problematic, with as many as 5,000 deaths annually in recent years.

  Read more about Clinical Briefs - Internal Medicine Alert – May 30, 2005