Internal Medicine Alert – March 15, 2003
March 15, 2003
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Moderation In All Things, Even Sleep
Women who habitually sleep 5 or fewer or 9 or more hours per night have an increased risk of coronary heart disease compared with those who sleep 7 or 8 hours a night. -
C-Reactive Protein Hits the Big Time
Elevated CRP levels are associated with inducible ischemia in patients with stable coronary disease, particularly among those not treated with beta-blockers or statins. -
Pharmacology Update: Alefacept (Amevive) for Psoriasis Treatment
Alefacept is a new biological agent for the treatment of moderate-to-severe plaque psoriasis. The drug, which targets T lymphocytes, is a fusion protein combining the binding site of lymphocyte function-associated antigen-3 and the Fc portion of human IgG1. -
Clinical Briefs
Syncope, Driving Recommendations, and Clinical Reality: Survey of Patients; Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease (COOPERATE): A Randomized Controlled Trial; Early Onset of Action and Efficacy of a Combination of Calcipotriene and Betamethasone Dipropionate in the Treatment of Psoriasis -
ECG Review: Chest Pain in a 21 Year Old
Clinical Scenario: The ECG in the Figure shows normal sinus rhythm at a rate of 80 beats/minute. The PR, QRS, and QT intervals are normal. There is an rSR pattern in lead III. The axis is +40°. There is no sign of chamber enlargement. The most remarkable finding on this tracing is the presence of subtle but real ST segment elevation in multiple leads including I, II, aVF, and V2 through V6. -
Pharmacology Watch: Smallpox Vaccination Guidelines Published by CDC
Smallpox Vaccination Guidelines Published by CDC; Nurses: Delay Vaccination Program; Viagra Effective for Depression Treatment; Finisteride/Doxazosin no Better than Placebo for Urinary Obstruction; Serevent Receives Dear Doctor Letter