Internal Medicine Alert – February 15, 2003
February 15, 2003
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Smoking and Lung Function of Lung Health Study Participants after 11 Years
Continuing smokers from the Lung Health Study 1 followed for a period of 11 years demonstrated a greater decline in lung function when compared to sustained quitters. -
Use of Selective Serotonin Reuptake Inhibitors and Risk of Upper Gastro-intestinal Tract Bleeding
SSRIs increase the risk of upper gastrointestinal bleeding, and this effect is potentiated by concomitant NSAID or aspirin use. -
Fluoroquinolones and Tendinopathie
The excess risk of Achilles tendon disorders attributable to fluoroquinolone use was estimated to be 3.2 cases per 1000 patient-years, with most of that increase accounted for by patients 60 years of age and older who concomitantly receive corticosteroids. -
Pharmacology Update: Adalimumab — Humira
The FDA has approved a new anti-tumor necrosis factor alpha (TNF alpha) drug for the treatment of rheumatoid arthritis (RA). -
Clinical Briefs
Prostate Cancer Screening; Can We Trust Home BP Measurement?; Systolic and Diastolic Dysfunction -
ECG Review: A Special Wave
The ECG in the Figure was obtained from a 68-year-old man admitted to the intensive care unit (ICU) for a drug overdose. In view of his ECG, what vital sign needs to be checked? How many ECG findings consistent with this patients clinical condition can you identify? -
Pharmacology Watch: FDA Issues ‘Black Box’ Warning Based on WHI Study
FDA Issues Black Box Warning Based on WHI Study; ALLHAT: Thiazide for Hypertension Treatment; Candesartan Effective Against Migraines; Cough! No Cold Relief from Echinacea; COX-2 Inhibitors and GI Benefits Could Be Overrated; FDA Actions