Infectious Disease Alert – December 1, 2021
December 1, 2021
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Surviving Sepsis 2021 Update
Some of the important changes include clearer differentiation of sepsis vs. septic shock and, for numerous recommendations, changing the strength and quality of evidence to support many.
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Pediatric Pneumonia — Diagnostic and Therapeutic Stewardship
A randomized, multicentered trial in the United Kingdom and Ireland showed children receiving amoxicillin for community-acquired pneumonia perform similarly well with lower dose (35-50 mg/kg/day vs. 75-90 mg/kg/day) and shorter duration (three vs. seven days) treatments.
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Melioidosis in the United States
Four cases of melioidosis in four states occurred and at least one was traced to a contaminated commercial aromatherapy product.
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Fluvoxamine Reduces the Risk for Hospitalization from COVID-19
A randomized, placebo-controlled trial found fluvoxamine (100 mg twice a day for 10 days) reduced the risk for hospitalization among high-risk outpatients diagnosed with COVID-19.
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An Outbreak of Injection Site Mycobacterium porcinum Infections After Vaccination in the Workplace
Vaccine (non-COVID-19) contamination as a result of improper handling led to injection site infections due to Mycobacterium porcinum, a rapid growing non-tuberculous mycobacterium present in the environment.
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Missing the Diagnosis of Congenital Syphilis
The diagnosis of congenital syphilis was delayed until the post-neonatal period in 2.2% of infants born in the United States from 2014-2018.
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Infectious Disease Alert Updates
Risk of COVID-19 During Air Travel; Symptoms Post-COVID: Loss of Taste in One in Seven; Effectiveness of Cloth and Surgical Masks Against SARS-CoV-2.