Infectious Disease Alert – May 1, 2019
May 1, 2019
View Issues
-
Oral Antibiotics Are Noninferior to Intravenous for Bone and Joint Infections
In a randomized, controlled trial of adult patients with bone or joint infections, researchers found oral antibiotic therapy was noninferior to intravenous therapy based on treatment failure at one year.
-
Viruses, Food Allergies, and Childhood Wheezing
Infants with severe bronchiolitis sometimes develop subsequent recurrent wheeze and asthma. Among infants hospitalized with bronchiolitis, the risk of developing asthma is greatest in those with rhinovirus C infection, especially if they also are sensitized with IgE against foods.
-
When to Screen for and Treat Asymptomatic Bacteriuria
New guideline recommendations indicate that the only unequivocal indications for screening and treatment of asymptomatic bacteriuria are pregnancy and undergoing endoscopic urologic procedures associated with mucosal injury.
-
Corticosteroid Administration in Sepsis May Be Associated With Lower 28-Day Mortality
In this systematic review and meta-analysis of randomized, controlled trials comparing administration of corticosteroids with placebo or standard supportive care in sepsis, corticosteroids were associated with reduced 28-day mortality.
-
Staphylococcus aureus Bloodstream Infections in the United States
Although the rate of hospital-onset MRSA bacteremia has decreased since 2012, the rate of decrease has slowed. The National Action Plan goal of a 50% reduction by 2012 compared to 2015 seems out of reach.
-
Infectious Disease Alert Updates
Multi-Modal Interventions for Controlling CRE: Which Is Best? Antimicrobial Resistance Genes — in the Arctic; Updated PEP Guidelines for Hepatitis A Vaccine