Infectious Disease Alert – July 1, 2018
July 1, 2018
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Antibiotic Use in Infancy Associated With Allergic Disease During Childhood
In a large population-based study, antibiotic use during the first six months of life was associated with a two-fold increase in asthma and a 1.5-fold increase in allergic disease during early childhood.
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Rotavirus Vaccine and Intussusception
Using active surveillance, researchers enrolled 717 infants with intussusception from sub-Saharan Africa. The risk of intussusception was no higher in those who received the monovalent rotavirus vaccine than in non-immunized infants.
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VRE and MRSA: Time to Assign Contact Precautions to the Dust Heap of History
In the context of other horizontally implemented, effective infection prevention measures, the use of contact precautions for most patients colonized or infected with MRSA or VRE fails to provide benefit.
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Reduced Noninfectious Adverse Events After Discontinuation of Contact Precautions in Patients Colonized or Infected With MRSA and/or VRE
Discontinuation of contact precautions for patients colonized or infected with either MRSA or VRE is associated with a decrease in rates of noninfectious adverse events.
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Oral Antibiotics May Increase the Risk for Nephrolithiasis
A case-control study found that receipt of an oral antibiotic in the preceding three to 12 months was associated with nephrolithiasis. The risk persisted up to five years, and younger patients were at increased risk.
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Why IDSA Did Not Support the Surviving Sepsis Campaign
The Infectious Diseases Society of America withheld its support for the Surviving Sepsis guidelines. The general concerns included vagueness and inconsistency in definition of sepsis, “one size fits all” prescription of time to administer antibiotics, lack of clarity around drawing blood cultures through IV catheters, recommendation of combination antibiotics, lack of definition around when to use procalcitonin levels, when and how to use pharmacokinetic and pharmacodynamic data effectively, prolonged antibiotic “prophylaxis,” and duration of therapy.
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Infectious Disease Alert Updates
Utility of GI Multiplex Assay; ‘The World Is Covered by a Thin Layer of Feces’