Infectious Disease Alert – April 1, 2016
April 1, 2016
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Trimethoprim-sulfamethoxazole versus Placebo for Skin Abscesses After Incision and Drainage
A multicenter, double-blind, randomized clinical trial found that a 7-day course of trimethoprim-sulfamethoxazole following incision and drainage (I&D) resulted in a higher rate of cure for skin abscesses compared to I&D and placebo (80.5% vs 73.6%, respectively; P = 0.005).
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Pediatric Coccidioidomycosis in California, 2000-2012
The incidence of pediatric coccidioidomycosis in California has increased significantly from 2000 until 2012, along with hospitalization for complicated disease. Latino children were most commonly infected, but African-American children were significantly more likely to be hospitalized.
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Antibiotic Use in Treatment of Children with Uncomplicated Severe Acute Malnutrition
Universal antibiotic use in the community-based treatment of uncomplicated severe acute malnutrition in children likely is not necessary in regions where suitable access to healthcare facilities is available.
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Saccharomyces Cerevisiae var boulardii ( S. boulardii ) and Antibiotic-associated Diarrhea
Saccharomyces boulardii administration failed to prevent antibiotic-associated diarrhea in a large randomized trial.
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Improve Treatment for Community-acquired Pneumonia
In patients with suspected community-acquired pneumonia, early chest CT significantly changed management decisions.
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Infectious Disease Alert Updates
TB in Captive Elephants in the United States; TB Skin Testing and IGRA: An Ongoing Source of Confusion; LASIK, Humidifiers, and Mycobacterium chelonae Ocular Infections