Infectious Disease Alert 2012-03-01

Abstract & Commentary: Oral HPV: A Potential Time Bomb for Cancer Development, Especially in Men

Gillison and colleagues examined the prevalence of oral human papillomavirus (HPV) infections in civilian non-institutionalized individuals 14 69 years of age in the U.S. by conducting a cross-sectional study as part of the National Health and Nutrition Examination Survey (NHANES).

Abstract & Commentary: MDR-Gram-Negative Bacteria in a U.S. Hospital in Afghanistan

US and Afghan patients with positive bacterial culture results from Sept 2007 through August 2008 were reviewed. 266 patients had 411 isolates identified during the study period.

Abstract & Commentary: Emerging Nipah Virus causes Outbreak in Bangladesh Linked to Bat Reservoir

It has been over 10 years since a deadly paramyxovirus known as the Nipah virus emerged in Asia. Over the subsequent decade there has been multiple outbreaks. Some traditional practices like drinking raw date sap are hard to break.

Beta-Lactam Therapy of Urinary Tract Infection Fails Again

The increasing prevalence of antibiotic resistance in urinary pathogens has led Hooton and colleagues to examine the efficacy of a relatively broad spectrum orally administered cephalosporin in the treatment of uncomplicated cystitis.

Antibiotics no Better than Placebo against Acute Rhinosinusitis

Garbutt and colleagues performed a randomized placebo controlled trial designed to evaluate the efficacy of antibiotic therapy in patients with a clinical diagnosis of acute rhinosinusitis at 10 primary care practices in St. Louis.

Abstract & Commentary: Absent Influenza Vaccine Response in Rituximab-treated Lymphoma Patients

The concern regarding influenza infection is high in cancer patients since the rate of infection is considerably higher and mortality is four times greater than in the general population.

Cryptococcosis in Previously Normal Adults: NIH Study Seeking Participants

Abstract & Commentary: Patients Placed in Contact Isolation Are at Increased Risk for Delirium

To examine the association between being placed in contact isolation and delirium, Day and colleagues at the University of Maryland Medical Center reviewed administrative data on all patients admitted during a 2-year period ending in 2009.

Updates By Carol A. Kemper, MD, FACP

Labial HSV is a remarkably common infection, and is now believed to infect ~70% of the population in the U.S.. Many of these people have only an infrequent outbreak or are unaware of their latent infection.

Pharmacology Watch: Dutasteride and Low-Risk Prostate Cancer

In this issue: New treatment for prostate cancer; avastin and breast cancer; new CMS disclosure rule; and FDA actions.

Clinical Briefs in Primary Care supplement

Infectious Disease Alert – March 1, 2012

March 1, 2012