Infectious Disease Alert – July 1, 2010
July 1, 2010
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World Cup 2010: Anticipated Infections in Travelers to South Africa
Before the 2010 FIFA World Cup competition began, it was anticipated that more than 350,000 visitors, including many from the United States, would descend upon South Africa. -
Acinetobacter Spreads its Wings
We have all watched as acinetobacter morphed from an infrequently seen isolate of little clinical consequence to a frightening pathogen. Microbiologists used to recover Acinetobacter lwoffii from vaginal secretions in the days when we thought, incorrectly, that gram-negative rods were pathogens in that site. -
Genome Determinants of HIV-1 Set Point in African-Americans
Healthcare providers have been constantly amazed at the variation in response to infection with HIV-1. In our clinic, we now routinely see elderly patients who have been on various antiretroviral regimens over the years but still persist with high CD4 counts and low viral loads. -
Bacterial Enteritis and Childhood Intussusception
A retrospective cohort study was conducted of all children age birth to five years enrolled at a Department of Defense treatment facility between January 1998 and December 2005, who were diagnosed with bacterial enteritis. -
Diagnostic Accuracy of Clinical Signs and Symptoms for Serious Bacterial Infection in Young Febrile Children
A two-year prospective cohort study of children less than five years of age presenting with a febrile illness (¡Ý 38.0¡ã C) to a single emergency department in Australia, used a standardized clinical evaluation with a mandatory entry for 40 clinical features between July 1, 2004, and June 30, 2006. -
Anthrax in Heroin Users
A critically ill patient, who was a heroin user, was admitted to a hospital in Scotland in December 2009 and was found to be infected with Bacillus anthracis. -
Early vs. Delayed Initiation of HAART in Patients with Cryptococcal Meningitis
This prospective, open-label, randomized clinical trial was conducted at a large tertiary teaching hospital in Harare, Zimbabwe, in adult ART-naïve HIV-infected patients who received a first CM diagnosis. -
Cytokine Signaling and Susceptibility to Infectious Diseases
In this study, 8,402 patients from seven case-control series were examined in this trial. The series included Kenyan children with bacteremia, patients with tuberculosis (TB) in Malawi, Hong Kong, and Gambia, and patients with severe malaria in Gambia, Kenya, and Vietnam. Standard methods for genotyping selected genes in PBMCs were employed. -
Updates by Carol A. Kemper, MD, FACP
The authors describe a previously healthy 44-year-old woman who presented with bacterial meningitis. On presentation, she was alert but complained of high fever and meningismus. She had no other neurologic symptoms. -
Pharmacology Watch: PPIs, Clostridium difficile, and Bone Fractures
In this issue: New reports about proton pump inhibitors and the effects of gastric suppression, pioglitazone vs vitamin E for non-alcoholic steatohepatitis, metformin and vitamin B12 deficiency, and FDA Actions. -
Clinical Briefs in Primary Care supplement