OB/GYN Clinical Alert – June 1, 2024

The Role of Probiotics and Synbiotics for Management of Gestational Diabetes

Probiotics and synbiotics have shown promise in reducing insulin resistance and enhancing glycemic control, blood lipid profiles, and inflammation among women with gestational diabetes mellitus (GDM). Although they hold potential as a treatment option for GDM, conclusive recommendations await larger, well-designed randomized controlled trials with extended follow-up periods.

Medication Abortion via Telehealth in the United States

A prospective study of U.S. patients obtaining medication abortion through telehealth platforms demonstrated high effectiveness (97.7%; 95% confidence interval [CI], 97.2% to 98.1%) and safety (99.8%; 95% CI, 99.6% to 99.9%).

Progestins and Meningioma Risk: What Do the Data Say?

The authors of this study sought to determine whether there was a relationship between progestins and central nervous system meningiomas.

Estradiol Valerate-Dienogest and VTE Risk in Combined Oral Contraceptives

A pooled analysis comparing the risk of venous thromboembolism associated with combined oral contraceptives (COC) found significantly decreased venous thromboembolism risk in estradiol valerate-dienogest COCs compared with ethinyl estradiol-levonorgestrel COCs (propensity score-stratified hazard ratio, 0.46; 95% confidence interval, 0.22-0.98).