Internal Medicine Alert – October 30, 2022

Hot Trials from the European Society of Cardiology Annual Congress

Some highlights from two key studies presented in Barcelona, Spain, between Aug. 26 and Aug. 29, 2022, along with Dr. Crawford’s personal commentary on both.

Family Members of Critically Ill Patients with SARS-CoV-2 Pneumonia Have a High Burden of Symptoms of PTSD

This multicenter cohort study found a high incidence of post-traumatic stress disorder symptoms among family members of COVID-19 patients at three months after the index intensive care unit admission.

Clinical Significance of Mitral Annular Calcification

Researchers found mitral annular calcification to be uncommon, and few experienced associated moderate to severe mitral stenosis or regurgitation. However, the latter group recorded a high mortality rate over three years follow-up, which was significantly lower in those who underwent valve interventions, even when corrected for younger age, fewer comorbidities.

Antibiotic Resistance: We Were Doing Great and then COVID Happened

After improvement, antimicrobial resistance in the United States significantly increased.

Dextromethorphan/Bupropion (Auvelity)

Auvelity can be prescribed to treat major depressive disorder in adults.