Internal Medicine Alert – August 15, 2024

Comparing Antidepressants’ Effects on Weight Gain

This observational study finds that, compared to sertraline, six-month weight gain is higher in patients prescribed other antidepressants in the same category (paroxetine, citalopram, escitalopram) as well as in patients prescribed duloxetine and venlafaxine, similar in patients prescribed fluoxetine, and lower in patients prescribed bupropion.

CVD Risk from Ketogenic Diets

A recent analysis of the UK Biobank data found that subjects on a low-carbohydrate, high-fat diet had higher levels of low-density lipoprotein cholesterol and apolipoprotein B, and an increase in incident major adverse cardiovascular events over a 12-year follow-up than subjects on a standard diet.

Dengue Is Surging, Including in the Americas

Dengue is surging, and cases have been acquired in the United States, including in Puerto Rico and Florida.

Donanemab-azbt (Kisunla)

The U.S. Food and Drug Administration has approved the third anti-amyloid beta monoclonal antibody for the treatment of Alzheimer’s disease, following aducanumab and lecanemab.

The Cath was “Clean!”

The featured electrocardiogram was obtained following successful resuscitation from cardiac arrest. Although echo done soon after showed akinesis of the anterior wall, no significant coronary narrowing was seen on cardiac catheterization. Can you explain? What is this phenomenon called?

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