Infectious Disease Alert – September 1, 2024

Mortality in Sepsis Patients Treated with Piperacillin-Tazobactam vs. Cefepime

A retrospective cohort study that included more than 7,000 patients with sepsis and no clear indication for anti-anaerobic coverage found receipt of piperacillin-tazobactam was associated with higher mortality and increased duration of organ dysfunction compared to cefepime.

Delusional Infestation

Delusional infestation, previously known as delusional parasitosis, is a condition with which patients believe that their bodies are infested with abnormal living organisms or non-living substances. Many patients can recover with a good therapeutic clinician-patient relationship and, usually, the use of risperidone, aripiprazole, or olanzapine.

Extensively Drug-Resistant Shigella on the Rise

The prevalence of Shigella resistant to azithromycin, ciprofloxacin, ceftriaxone, trimethoprim-sulfamethoxazole, and ampicillin is increasing.

Effectiveness and Safety of Transitioning to Oral Antibiotics in Solid Organ Transplant Recipients with Uncomplicated Gram-Negative Bloodstream Infection

In a retrospective observational study, transitioning to oral antibiotics was demonstrated to be as effective and safer in solid organ transplant recipients with uncomplicated gram-negative bacteremia as compared with completion of therapy with intravenous antibiotics.

Out of Africa Again? A New Version of Mpox

A novel mpox clade has emerged in Africa and has the potential for a global epidemic.

Infectious Disease Alert Updates

Abandoning Universal COVID Admission Screening; Does Obesity Affect HIV Drug Levels? Eat Your Fruits and Vegetables!