Critical Care Alert – September 1, 2022

COVID-19 Infection Course Worse in Patients Receiving Anti-CD20 Treatment

In this retrospective cohort, patients receiving anti-CD20 treatment had worse clinical outcomes, including mortality, in addition to longer durations of infectivity and higher rates of relapse.

A Fluid Bolus Peri-Intubation Does Not Prevent Cardiovascular Collapse

In this randomized pragmatic clinical trial, a peri-intubation intravenous fluid bolus administered to critically ill adults undergoing tracheal intubation with positive pressure ventilation did not significantly reduce the risk of cardiovascular collapse.

Outcomes of COVID-19-Associated Acute Myocarditis

In a review of COVID-19-associated acute myocarditis, investigators learned it is a rare complication that can occur without concomitant pneumonia, and frequently presents as cardiogenic shock. With supportive therapy, the short-term mortality rate is low.

Cirrhosis and Infections

Infections in patients with cirrhosis are frequent and potentially lethal, with pneumonia associated with the highest risk for mortality.