Critical Care Alert – November 1, 2022

Updates in Stress Ulcer Prophylaxis

The development of esophageal, gastric, and duodenal erosions or ulcers may increase the morbidity and mortality of critically ill patients. Stress ulcer prophylaxis can be administered pharmacologically to prevent gastrointestinal bleeding from the ulcers.

Intravenous Fluids in ICU Patients with Septic Shock: Is Restriction the Answer?

In an international, randomized trial of 1,554 patients with septic shock who had already received > 1 liter of intravenous fluids, patients assigned to the restrictive-fluid group compared to the standard-fluid group did not have reduced mortality at 90 days.

Modifiable Factors Play a Significant Role in the Performance of Spontaneous Awake and Breathing Trials

In this secondary analysis of data from a national intensive care unit collaborative, various non-modifiable and modifiable factors were associated with performance of spontaneous awake and breathing trials.