Critical Care Alert – June 1, 2023
June 1, 2023
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Management of COPD Exacerbations in the ICU: What’s New?
Chronic obstructive pulmonary disease (COPD) exacerbations continue to negatively affect health status, including disease progression and mortality, making optimization of the critically ill COPD patient imperative.
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Adjuvant Systemic Corticosteroid Therapy in Hospitalized Patients with Community-Acquired Pneumonia
This systematic review and meta-analysis of 16 randomized controlled trials (RCTs) studied the use of adjunctive corticosteroid therapy in community-acquired pneumonia. All-cause mortality, intensive care unit admission, and incidence of adverse events were similar in patients who received corticosteroids compared to standard care. However, the corticosteroid therapy group had a lower incidence of progression to mechanical ventilation.
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Steroids and Pneumonia — So Meta?
In a multicenter, randomized, placebo-controlled trial, hydrocortisone reduced mortality in patients with severe community-acquired pneumonia.