Articles Tagged With: mortality
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Anticoagulation Plus Antiplatelet Therapy in Chronic Atherosclerosis
An analysis of the COMPASS trial for the secondary endpoint of mortality showed the combination of low-dose rivaroxaban and aspirin significantly lowered the all-cause mortality rate vs. low-dose aspirin alone.
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MRI Changes and Functional Outcomes Among Adults with Severe HSV Encephalitis
Herpes simplex virus is a common cause of encephalitis worldwide. When treated promptly, the mortality rate decreases from 70% to 15%, but many patients remain disabled. This multicenter cohort study analyzed magnetic resonance imaging in patients diagnosed with herpes simplex encephalitis admitted to the intensive care unit to identify factors associated with poor outcome at 90 days.
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Mortality and Costs of Status Epilepticus
In an analysis of a large group of patients hospitalized with status epilepticus, based on an administrative database, patients who required a third line of intravenous anesthetic agents had the highest mortality and highest hospital costs.
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Iron Therapy for Acute Heart Failure
Giving intravenous ferric carboxymaltose to stabilized post-acute heart failure patients with iron deficiency improved quality of life vs. placebo-treated patients within four weeks, which persisted during subsequent therapy for up to 24 weeks. -
Anticoagulation Plus Antiplatelet Therapy in Chronic Atherosclerosis
An analysis of the COMPASS trial for the secondary endpoint of mortality showed the combination of low-dose rivaroxaban and aspirin significantly lowered the all-cause mortality rate vs. low-dose aspirin alone. -
Vaccines Are Available, but the Search for COVID-19 Therapeutics Continues
Right after the FDA issued an emergency use authorization for one drug, feds pressed pause on distributing another. -
Using Procalcitonin to Limit Antibiotic Treatment for Sepsis Reduces Infection-Related Adverse Events
By shortening the duration of antibiotic therapy, a procalcitonin-guided protocol decreased the rate of infection-associated adverse effects, decreased costs, and reduced mortality in patients with sepsis. -
The Effect of Antiviral Drugs on COVID-19 Outcomes and Mortality
The WHO Solidarity Trial Consortium found remdesivir, hydroxychloroquine, lopinavir, and interferon regimens produced “little or no effect” on relevant outcomes. -
U.S. COVID-19 Deaths 58% Higher Than Reported
With many COVID-19 deaths unreported in the United States, researchers estimate the actual death toll of the pandemic is closer to 1 million than the 574,043 reported from March 1, 2020, to May 3, 2021. Looking at excess mortality data, researchers at the University of Washington’s Institute for Health Metrics and Evaluation calculated 905,289 COVID-19 deaths occurred in the U.S. during that period. That is 58% higher than the official numbers. -
Rapid Mortality Reviews Improve Quality and Patient Safety
Staff at a California hospital found rapid mortality reviews conducted soon after a patient death resulted in the treatment team identifying opportunities to improve the patient’s care in more than 40% of the cases. The team conducting the rapid mortality reviews concluded this technique can offer advantages over the standard retrospective case reviews, provider surveys, and structured morbidity and mortality conferences.