-
There is emerging evidence that maintenance chemotherapy is of value for ovarian cancer patients after surgery and remission-induction chemotherapy.
-
A meta-analysis of existing data on the primary management of operable breast cancer in elderly women demonstrates that when the approach is hormonal (tamoxifen) rather than surgery, local recurrence is higher. Overall survival, however, was not different.
-
In a series of 16 patients with CML blast crisis, treatment mitoxantrone, etoposide, and imatinib on four different schedules was studied in a phase I/II trial.
-
-
-
-
Although spontaneous intracranial hypotension (SIH) generally causes a benign, self-limited, postural headache, subdural hematomas may occur in SIH with serious sequelae.
-
In addition to previously identified antibodies that cause limbic encephalitis, novel antibodies directed against cell membrane antigens may cause many of the "antibody-negative" cases, and these cases seem to respond favorably to immunosuppressive treatment.
-
Torcetrapib, a cholesteryl ester transfer protein (CETP) inhibitor, has been in development by Pfizer for nearly 15 years.
-
These 2 clinical trials comparing Standard and New Antiepileptic Drugs (SANAD) showed that for partial epilepsy, lamotrigine was clinically better than carbamazepine, and that for generalized and unclassifiable epilepsy, valproate was better tolerated than topiramate and more efficacious than lamotrigine.
