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A meta-analysis of 18 studies that have examined the usefulness of procalcitonin measurement in the diagnosis of sepsis finds that the diagnostic performance of this measurement is low and that the test cannot reliably distinguish sepsis from other causes of the systemic inflammatory response syndrome.
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MRI is more sensitive than CT for detecting acute ischemia and can detect acute hemorrhage with equal sensitivity to CT.
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Disturbance of sleep continuity, but not simple sleep deprivation, impairs pain inhibition and increases spontaneous pain.
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GlaxoSmithKline's rosiglitazone (Avandia) will receive a black box warning by the FDA because of concerns over heart failure associated with use of the drug.
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Surgery for a herniated lumbar disc with sciatica does not have a better long-term result than conservative therapy.
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A pilot study of human cervical disc transplantation has been shown to be surgically feasible, but requires further investigation.
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The rotigotine transdermal system (Neupro) is a safe and effective treatment for early Parkinson's Disease.