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Richards and colleagues representing the Canadian Multicentre Osteoporosis Study Research Group reported the effect of daily selective serotonin reuptake inhibitors (SSRIs) use in a prospective cohort study in 7 regional centers of 5008 adults over the age of 50.
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Ovarian cancer patients relapsing within 6 months of their primary therapy represent among the most challenging patients to treat. Generally, in this setting, most patients have only been exposed to one or two agents, yet they are phenotypically resistant to most chemotherapeutics, making drug discovery of paramount importance.
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Results of the Women's Healthy Eating and Living (WHEL) study were published in a recent issue of JAMA. In this multicenter, randomized controlled trial a total of 3088 women diagnosed with early-stage breast cancer (stage I-IIIa) within the previous four years were randomized to a diet rich in vegetables, fruit and fiber and low in fat, vs a regular diet.
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In a nested cohort analysis of a large Japanese sample, coffee drinking was associated with a decreased risk of death from hepatocellular carcinoma in all subjects, and specifically, those infected with hepatitis C virus.
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By analysis of two National Cancer Institute of Canada clinical trials for limited-stage small cell lung cancer, it was found that anemia was present in approximately one-third prior to treatment ...
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Fludarabine combined with cyclophosphamide was compared to fludarabine alone or chlorambucil as initial treatment for chronic lymphocytic leukemia (CLL) in a randomized multi-site trial.
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Circulating levels of sex steroids (estradiol, testosterone) and breast density (as determined by mammography) are known risk factors for the development of breast cancer.
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Patients with peripheral artery disease are at high risk for cardiovascular complications. Antiplatelet drugs are routinely prescribed for these patients, but is adding an oral anticoagulant of value?
