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An outbreak of 140 human cases of West Nile Virus in Kern County, California (better known for its increased risk of coccidioidomycosis), during the summer of 2007, prompted Reisen et al to look for possible causes.
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Hospital-acquired pneumonia (HAP) represents the second most common nosocomial infection, accounting for 15% of all hospital-associated infections.
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In this issue: The JUPITER trial causes a stir; ACP practice guideline for antidepressant use; testosterone for low libido; continued shortage of Hib vaccine; FDA Actions.
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Investigators and clinical trial associates sometimes miss the more subtle signs of vulnerabilities among potential study participants.
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Clinical research sites are continuing to struggle finding and retaining trained staff in an environment in which physicians, researchers, and nurses are in ever shorter supply.
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Most clinical trial managers face the familiar problem of finding the right employees to handle increasingly difficult clinical research work and then keeping the best employees for more than a year or two.
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The risk of recurrent venous thromboembolism (VTE) during extended anticoagulant therapy for thrombophilia remains poorly defined. Investigators analyzed 661 patients with idiopathic VTE who had been randomized to extended prophylaxis after three months of initial anticoagulation using either low intensity (INR 1.5-1.9) or standard intensity (INR 2.0-3.0) anticoagulation.
