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In this study, 165 clinical isolates of rapidly growing mycobacteria (including M. abscessus, M. chelonae, M. peregrinum, M. fortuitum, M. mucogenicum, M. mageritense, M. alvei, M. smegmatis, M. porcinum, M. septicum, and M. wolinskyi) were tested for in vitro susceptibility to tigecycline and 10 other antibiotics (erythromycin, clarithromycin, azithro-mycin, ciprofloxacin, levofloxacin, amikacin, tobra-mycin, cefoxitin, doxycycline, and trimethoprim-sulfamethoxazole) using a broth microdilution method.
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Enterococcus used to be considered the caboose of pathogens; maybe it mattered, but it still was at the far rear.
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A retrospective review of one major continental United States (CONUS) tertiary care medical center's plastic surgery department's experience in the management of combat wounds was performed and included all cases seen between April 2003 and December 2005. Of the 68 patients treated, 16.2% sustained injuries to the head/face/neck, 61.8% had lower extremity injuries, 29.4% had upper extremity injuries, 15.6% had both upper and lower extremity injuries, and 35.9% had multiple sites of injuries.
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Faced with limited data about acute mountain sickness in children who travelled rapidly to high altitudes, Swiss researchers studied symptoms in 48 children (ages 10-17, mean age 13) who traveled 2.5 hours from low altitude (568 meters) to 3,450 meters (approximately 11,200 feet).
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In this issue: Individualization of therapy with pharmacogenetics; the rate vs rhythm debate; the FDA's Risk Evaluation and Mitigation Strategy; FDA actions.
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I recall rounding on the oncology ward as a medical student. The prognosis in those days was bad for nearly every patient. Children with acute lymphoblastic leukemia were expected to live less than one year. Adults with acute myeloblastic leukemia, less than three months. What a difference in the past three decades.
With longer survival, however, there are more patients presenting with life-threatening emergencies related to their treatment and tumor.
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In older women and men, all low-trauma fractures were associated with increased mortality risk for at least 5 years. Subsequent fracture increased that risk.
