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By simplest definition, shock is a state of inadequate substrate delivery at the cellular level.
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Aspirin dose and cardioprotection; uncovering modafinil's abuse potential; proton-pump inhibitors and clopidogrel; FDA actions.
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The need for participation of the primary care physician in the treatment of sleep apnea has become much more apparent in recent years.
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In a randomly selected population of post-menopausal breast cancer patients treated with either tamoxifen or anastrozole, discordance was found between self-reported adherence to prescribed treatment and actual records of prescription fills provided by local hospital and physician records. The findings support further research in developing strategies to better understand and overcome non-adherence.
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In a multicenter, randomized, placebo-controlled phase III trial, imatinib (400 mg/d) administered for one year was demonstrated to enhance progression-free survival for patients with gastrointestinal stromal tumors. This study was the basis for the FDA approval for such treatment in this setting.
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Unmutated immunoglobulin variable heavy chain (IgVh) in patients with chronic lymphocytic leukemia is associated with worse outcome.
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