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Most experts agree that offering flu vaccinations is a good idea, but the issue of requiring them can stir up a debate.
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The "black box" warning on medications is the health care system's strongest way to say, "Danger! Take extreme caution with this drug!" But a recent report suggests that your physicians might not be fazed by the warning.
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FDA Recommends Approval of Muraglitazar, But May Need To Reconsider; Which Antipsychotics Are More Dangerous?; Should CPOE Undergo Evaluation?; New Treatment for Tennis Elbow; FDA Actions
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Prostate cancer is one of the leading causes of cancer in men, both in this country and in Europe. Due to the introduction of the prostate specific antigen blood test (PSA test), the ability to diagnose prostate cancer well before signs or symptoms of the disease develop has been realized. Following its introduction, the PSA was endorsed widely and recommended by many major public health organizations as a useful screening test.
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Despite increased toxicity, CT did not significantly reduce patient QOL when compared with cisplatin alone. Patient-reported QOL measures may be an important prognostic tool in advanced cervix cancer.
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The reproducibility of the proteomic profiling approach has yet to be established.
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In a phase II trial of bevacizumab and gemcitabine in patients with advanced pancreatic cancer, responses were observed in 21% and stable disease in 46%. Although the median overall survival was not dramatically superior to that reported for gemcitabine alone, there is rationale for proceeding to larger scale phase III trial of this combination.
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In this prospective study of 1754 medical patients receiving low molecular weight heparin (LMWH), Prandoni and colleagues found a 0.8% incidence of heparin induced thrombocytopenia. The incidence was similar to a prior study they performed in medical patients receiving unfractionated heparin (UFH). Prior heparin exposure was associated with an increased risk of HIT. These data raise the possibility that HIT occurs more commonly in medical patients than previously appreciated and the incidence may not necessarily be significantly lower than with UFH. Clinicians must remain aware of the possibility of HIT, even in patients receiving either LMWH or UFH.
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Surgical staging in patients presenting with grade 1 endometrial cancer significantly impacted postoperative treatment decisions in 29% of patients. Omitting lymphadenectomy in patients presenting with grade 1 endometrial cancer may lead to inappropriate postoperative management.
