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Dabigatran etexilate is an oral compound that is converted after absorption by a serum esterase to dabigatran, a direct competitive inhibitor of thrombin.
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Erratic intraindividual INR values on chronic warfarin therapy are thought to be due to variability in vitamin K intake in the diet. Thus, de Assis et al from Brazil hypothesized that a dietary, vitamin K management strategy would result in improved long-term anticoagulation as compared to traditional systems based upon drug-dose adjustments alone.
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Depression and pregnancy, new vaccine recommendations from the CDC, cortico-steroids and/or antivirals for Bell's palsy, rasagiline and Parkinson's disease, and FDA Actions.
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Many clinical trials have confirmed the benefit of early invasive therapy for high-risk patients presenting with acute coronary syndromes (ACS). However, the optimal timing of cardiac catheterization in this group remains unknown.
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The effects of coffee on the heart remain incompletely described. There are conflicting reports of coffee's effects on the incidence of coronary artery disease, heart failure (HF), atrial fibrillation, and glucose homeostasis.
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Eye trauma is a common chief complaint among emergency department (ED) pediatric patients. Although many eye injuries can be prevented by appropriate supervision of children's activities and the appropriate use of protective eyewear, eye injuries remain an important cause of visual loss in children.
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Oseltamivir (Tamiflu®) is an FDA-approved drug for the treatment and prevention of influenza. With the anticipated emergence of seasonal influenza virus cases in October, and the recent discoveries of novel H5N1 (avian) and 2009 H1N1 (swine) influenza viruses, it is imperative to understand how to appropriately dose oseltamivir.
