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These authors report on the unique presentation of a 17-year-old previously healthy woman who developed acute onset fever, headache, nausea, and vomiting. Lumbar puncture confirmed a cerebrospinal fluid pleocytosis, and blood and CSF (but not urine) cultures yielded Group B streptococcus (S. agalactiae).
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Which Antipsychotics Are More Dangerous?; Should CPOE Undergo Evaluation?; New Treatment for Tennis Elbow; FDA Actions
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Synopsis: Investigators reported finding the presence of a metallo-â-lactamase gene mediating resistance to multiple â-lactam antibiotics, including carbapenems, among multiple species of Gram-negative pathogens isolated from a single hospital in Australia.
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ADEP I-6 have a complex ring structure. ADEP-I is the primary natural product (factor A). ADEP-1 has congeners that have been optimized for antibacterial activity, with the addition of 2 fluorides, to produce a difluoronated phenylalanine side chain.
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Failure of initial antibiotic therapy is a well-known cause of morbidity and mortality in infections such as ventilator-associated pneumonia. However, the damage doesnt stop there. Inappropriate antibiotic empiric therapy can be a surprisingly costly and sometimes deadly consequence even for less serious infections.
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Health care workers are more likely to receive post-exposure treatment after a bloodborne pathogen exposure than they were 10 years ago, but management of their regimens still needs improvement, according to the Centers for Disease Control and Prevention (CDC) in Atlanta.
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Clostridium difficile continues to emerge in a more pathogenic form with a new epidemiological profile. Particularly disturbing are new reports in four states of infections in patients previously thought to be at low risk for C. diff.
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Synopsis: Three ICU patients receiving Saccharomyces boulardii (cerevisiae) therapy for treatment of Clostridium difficile colitis experienced fungemia. Review of 60 cases of S. cerevisiae fungemia reported in the literature found that risk factors included presence of a central venous catheter, intravenous or enteral alimentation, and receipt of S. cerevisiae as a probiotic.
