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In a clinical trial conducted in Mexico City, 162 women with systemic lupus erythematosus were randomized to treatment with 1 of 3 contraceptive methods: estrogen-progestin oral contraceptives, oral progestin-only, or a copper IUD. Disease activity remained equally mild and stable over 1 year in all 3 groups.
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Do Antidepressants Increase Risk of Suicide?; Can Viagra Improve Heart
Function?; A Dramatic Increase of Clostridium difficile; FDA Actions
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Late in the evening you receive a page about a patient who is fighting the ventilator. You are cross-covering and do not know the patient. Your sign-out sheet says only that she is 68 years old, has severe COPD complicated by pneumonia, and has been in the ICU for the last 3 days. No specific problems are mentioned.
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Do Antidepressants Increase Risk of Suicide?; Can Viagra Improve Heart Function?; A Dramatic Increase of Clostridium difficile; FDA Actions
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Propylene glycol is used as the carrier vehicle for a number of drugs including lorazepam and diazepam. It may cause metabolic abnormalities such as anion gap metabolic (usually lactic) acidosis and hyperosmolality.
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In this study from the University of Liverpool, Duffy and associates sought to determine whether the addition of intravenous aminophylline produced clinically important improvements in the rates of symptomatic recovery or increases in pulmonary function, and whether it shortened hospital stay, in comparison with standard therapy without aminophylline, among patients with COPD who were admitted with an exacerbation.
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