Twenty highly active patients with neuromyelitis optica (NMO) stabilized after treatment with mitoxantrone. All patients tolerated treatment without significant safety concerns. Mitoxantrone may be an option for NMO given its differential inhibitory effect on subsets of B-cells.
Early plasmapheresis and high-dose intravenous corticosteroids may be as effective as conventional oral corticosteroid therapy in the treatment of myasthenia gravis.
The applause sign is a nonspecific indicator of frontal lobe dysfunction and is not specific to Parkinsonian disorders.
A novel technique used to study deviations in the subjective visual vertical may assist in the localization of brainstem lesions.
Controversy remains regarding the optimal blood pressure early in the course of ischemic stroke.
Severe Vitamin D deficiency appears to worsen dementia and supplementation may be beneficial.
Escitalopram for menopausal hot flashes, rifaximin for IBS without constipation, herpes zoster vaccination, antiepileptics drugs and fracture risk, and FDA Actions.
