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A new autosomal-dominant genetic disorder is described that has similarities to sporadic motor neuron disease.
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ACEI/ARB therapy for AS; safety alert issued for dronedarone; statins and cancer risk; nesiritide and heart failure; and FDA actions.
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Based on data from the Nurses' Health Study II, the authors report that higher maternal intake of vitamin D during pregnancy may be associated with a lower risk of multiple sclerosis in their children.
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Evaluation of non-Parkinsonian carriers of the LRRK2 mutation associated with Parkinson's disease supports a model of pre-motor symptomatology, including impaired color discrimination and constipation, that could be related to pathology developing prior to that in the substantia nigra.
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Symptoms of muscle pain and discomfort are common with statin use, but weakness and creatine kinase elevation are unusual.
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Gabapentin enacarbil is effective for sleep disturbance in moderate-to-severe primary restless legs syndrome, but frequently causes sleepiness and dizzinesss.
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Payers are asking for more preauthorizations, even for services that previously didn't require them, reports Connie Campbell, director of patient access of Mercy Medical Center in Oshkosh, WI.
